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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1704
All Species:
33.33
Human Site:
S254
Identified Species:
61.11
UniProt:
Q8IXQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXQ4
NP_061029.2
340
38142
S254
K
D
E
E
H
I
L
S
G
R
D
K
R
L
A
Chimpanzee
Pan troglodytes
XP_509661
340
38139
S254
K
D
E
E
H
I
L
S
G
R
D
K
R
L
A
Rhesus Macaque
Macaca mulatta
XP_001094145
344
38614
S258
K
D
E
E
H
I
L
S
G
R
D
K
R
L
A
Dog
Lupus familis
XP_851499
342
38712
S256
K
D
E
E
H
V
L
S
G
R
E
K
R
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZC8
346
38936
S260
K
D
E
E
N
I
L
S
G
R
D
K
R
L
A
Rat
Rattus norvegicus
Q4V893
348
39156
S262
K
D
E
E
N
M
L
S
G
R
D
K
R
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514535
347
38704
S261
D
D
E
E
R
V
L
S
G
R
D
K
R
L
A
Chicken
Gallus gallus
NP_001006270
350
39239
S264
D
N
E
E
M
V
L
S
G
R
D
K
R
L
V
Frog
Xenopus laevis
NP_001089474
337
37926
S251
T
E
E
K
F
P
L
S
D
R
D
K
H
L
A
Zebra Danio
Brachydanio rerio
NP_001003473
405
45367
L318
A
K
D
D
V
P
R
L
S
Q
K
E
L
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996214
349
39457
A267
D
D
E
Q
E
S
M
A
K
R
H
K
K
K
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93591
297
33204
V224
D
A
R
Q
A
A
I
V
A
E
K
T
S
G
P
Sea Urchin
Strong. purpuratus
XP_796639
403
45460
R308
Q
E
R
G
G
K
S
R
K
K
E
A
G
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.3
91.5
N.A.
89.5
87.3
N.A.
64.2
68.8
63.2
47.1
N.A.
26.9
N.A.
27.6
37.9
Protein Similarity:
100
100
98.5
96.1
N.A.
93.6
93.3
N.A.
75.2
80
75.8
60.2
N.A.
41.5
N.A.
44.7
53.8
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
80
66.6
53.3
0
N.A.
26.6
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
66.6
26.6
N.A.
53.3
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
8
0
8
8
0
0
8
0
0
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
62
8
8
0
0
0
0
8
0
62
0
0
0
0
% D
% Glu:
0
16
77
62
8
0
0
0
0
8
16
8
0
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
0
0
62
0
0
0
8
8
0
% G
% His:
0
0
0
0
31
0
0
0
0
0
8
0
8
0
8
% H
% Ile:
0
0
0
0
0
31
8
0
0
0
0
0
0
0
0
% I
% Lys:
47
8
0
8
0
8
0
0
16
8
16
77
8
8
0
% K
% Leu:
0
0
0
0
0
0
70
8
0
0
0
0
8
70
0
% L
% Met:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
16
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
0
16
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
16
0
8
0
8
8
0
77
0
0
62
0
0
% R
% Ser:
0
0
0
0
0
8
8
70
8
0
0
0
8
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% T
% Val:
0
0
0
0
8
24
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _